Welcome to the Laboratory for Advanced Biopolymers and Nanomechanics of Proteins (LABNanoPro)!

Lab June 2020

Lab 2020. From left to right: Ionel, Smrithika, Luai, Sabita, Kim, Marina, Narayan, Binh, Annie and Joel.

Our lab is using cutting-edge single molecule force spectroscopy techniques to investigate the response of proteins to mechanical perturbations. Our research combines instrument development, protein engineering, covalent attachment chemistries, and computer programming to study the mechano-chemistry of proteins from single molecule to tissue organization. Located in the new Kenwood Interdisciplinary Research Center, our group has a brand new wet-lab section, fully equipped for protein engineering and surface chemistry, and measuring facilities, such as a fully operational custom-made magnetic tweezers and a microscope mounted tensile tester for biological tissues/materials, currently under development. For more information about our research of interests, please refer to our recent publications here.

July 7, 2021

Congratulations to Narayan for his successful PhD 


Congratulations to now Dr. Narayan Dahal for his successful defense! Narayan is the first Ph.D. student to graduate from
our lab. He developed new methods to study the mechanical response of proteins at single molecule level and successfully studied the binding of bacterial proteins to their ligands, how proteins operate during cellular mechano-transduction and
how muscle proteins respond to forces. We wish him all the
best in his future endeavors!

June 4, 2021

Good students get awards

Congratulations to our graduate students, Narayan Dahal for getting the Lichtman Award, which is given yearly to the best experimentalist student in the Physics Department, and to Sabita Sharma for receiving the Graduate Student Excellence Fellowship Award from the Graduate School. Also congrats to our undergraduate student, Naomi Raicu, for being offered an Quantum Undergraduate Internship by the Fermi National Accelerator Laboratory over the summer!

March 15, 2021

Our paper was featured on the front cover of The FEBS Journal

Our review article on the roles of mechanical protein unfolding invo, entitled Does protein unfolding play a functional role in vivo?, was  featured on the cover of the March 15, 2021 issue of The FEBS Journal.





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